Kavasogullari C, Demirel M, Roiatti I, Sari B. Methylene blue: a scoping review: biological effects in mitochondrial health, neuroprotection, aesthetic and regenerative medicine. Longevity. 2026;7(1):2674547. doi:10.1080/30653495.2026.2674547.
This scoping review maps research on methylene blue across mitochondrial biology, neuroprotection and regenerative medicine. It brings together laboratory, animal and early human evidence rather than establishing a treatment recommendation.
The review included 26 studies. Biological mechanisms and preliminary findings may help guide future research, but they do not establish routine clinical benefit for longevity or aesthetic use. Further clinical trials are needed to clarify efficacy and long-term safety.
Published in Longevity on 29 May 2026. Authors: Cemal Kavasogullari, Mucadiye Demirel, Isabella Roiatti and Bengi Sari. Dr Kavasogullari contributed conceptualisation, supervision, and manuscript review and editing.
This page is a brief editorial summary, not the full paper or individual medical advice.